Cryptic crossword clue
& 10 Bear with ‘strong handshake’ used on reckless drug-taker? 7,4

The most common and most likely answer to this crossword clue is the 7 letter word STOMACH

S
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O
M
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H


Buddy explains!

The straight part
We know that "(something) used on reckless drug-taker" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case (something) used on reckless drug-taker = stomach.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does STOMACH mean?

STOMACH noun
  1. An organ in animals that stores food in the process of digestion.
  2. The belly.
  3. Pride, haughtiness.
  4. Appetite.
  5. Desire, appetite (for something abstract).
STOMACH verb
  1. To tolerate (something), emotionally, physically, or mentally; to stand or handle something.
  2. To be angry.
  3. To resent; to remember with anger; to dislike.
  4. To turn the stomach of; to sicken or repel.

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