The most common and most likely answer to this crossword clue is the 4 letter word HUGE
I've seen this crossword clue in The Guardian
H
U
G
E
More clues leading to the result HUGE
- Keep close to English giant
- Great writer needs energy to replace old ending
- Embrace European of substantial proportions
- Enormous shade screening top of garden
- Mammoth‘s initially grey in colour
- Embrace electronic giant
- Theurgies regularly conjure up giant
- Cuddle close to Cookie Monster
- 11 Tremendous
- Mammoth seen in press reaching Estonia’s capital
Buddy explains!

The straight part
We know that "Tremendous/ acceleration in 2" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case tremendous/ acceleration in 2 = huge.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does HUGE mean?
HUGE adjective- Very large.
- Distinctly interesting, significant, important, likeable, well regarded.