The most common and most likely answer to this crossword clue is the 6 letter word ALPACA
I've seen this crossword clue in The Times
A
L
P
A
C
A
More clues leading to the result ALPACA
- Holding a cape, mount a grazing animal
- Mountain animal covering Andes, primarily
- A top US city rejected source of wool
- A cat having tail nibbled by mountain creature
- Animal, better left in two areas, sent west
- A better article in French about S American mammal
- A large group of hunters ending off a domesticated mammal
- Required from kleptomaniac, a plan to return high-end fabric
- American star wearing nothing upstaged by a furry animal
- Mountain, cold in two areas, and beast there?
Buddy explains!

The straight part
We know that "S American mamma" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case s american mamma = alpaca.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ALPACA mean?
ALPACA noun- A sheep-like animal of the Andes, Vicugna pacos, in the camel family, closely related to the llama, guanaco, and vicuña.
- Wool from the alpaca.