Cryptic crossword clue
A biochemical substance that’s no longer in appendages to organs 6

The most common and most likely answer to this crossword clue is the 6 letter word ADNEXA

A
D
N
E
X
A

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The straight part
We know that "appendages to organs" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case appendages to organs = adnexa.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ADNEXA mean?

ADNEXA noun
  1. The appendages of an organ, such as the fallopian tubes of the uterus.

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