Cryptic crossword clue
A bit of work in a search for enzyme 6

The most common and most likely answer to this crossword clue is the 6 letter word KINASE

I've seen this crossword clue in The Guardian
K
I
N
A
S
E

Buddy explains!

The straight part
We know that "enzyme" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case enzyme = kinase.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

Crossword Answer definitions

KINASE noun
  1. Any of a group of enzymes that transfer phosphate groups from high-energy donor molecules, such as ATP, to specific target molecules (substrates), in a process termed phosphorylation.

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