Cryptic crossword clue
A commotion’s beginning in church — natural to laugh 10

The most common and most likely answer to this crossword clue is the 10 letter word CACHINNATE

I've seen this crossword clue in The Times
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The straight part
We know that "to laugh" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case to laugh = cachinnate.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CACHINNATE mean?

CACHINNATE verb
  1. To laugh loudly, immoderately, or too often.

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