Cryptic crossword clue
A condition causing swelling on one rodent 6

The most common and most likely answer to this crossword clue is the 6 letter word AGOUTI

I've seen this crossword clue in The Guardian
A
G
O
U
T
I


Buddy explains!

The straight part
We know that "rodent" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case rodent = agouti.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does AGOUTI mean?

AGOUTI noun
  1. A rodent similar in appearance to a guinea pig but having longer legs, of the family Dasyprocta.
  2. A fur containing a pattern of pigmentation in which individual hairs have several bands of light and dark pigment with black tips; any of several genes responsible for this pigmentation.

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