The most common and most likely answer to this crossword clue is the 9 letter word ACIDIFIED
I've seen this crossword clue in The Times
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The straight part
We know that "become sour" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case become sour = acidified.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
Crossword Answer definitions
ACIDIFIED verb- To make something (more) acidic or sour; to convert into an acid.
- To neutralize alkalis, as to acidify sugar
- To sour, to embitter.