Cryptic crossword clue
A contact from Test and Trace taking off? 5

The most common and most likely answer to this crossword clue is the 5 letter word APING

I've seen this crossword clue in The Daily Telegraph
A
P
I
N
G


Buddy explains!

The straight part
We know that "taking off" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case taking off = aping.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does APING mean?

APING verb
  1. To behave like an ape.
  2. To imitate or mimic, particularly to imitate poorly.
APING noun
  1. Foolish imitation or mimicry.

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