Cryptic crossword clue
A convolution of brain surgery ordered without hesitation 5

The most common and most likely answer to this crossword clue is the 5 letter word GYRUS

I've seen this crossword clue in The Times
G
Y
R
U
S

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The straight part
We know that "A convolution of brain" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case a convolution of brain = gyrus.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does GYRUS mean?

GYRUS noun
  1. A ridge or fold on the cerebral cortex.

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