Cryptic crossword clue
A couple of girls of fussy disposition 7

The most common and most likely answer to this crossword clue is the 7 letter word FINICKY

I've seen this crossword clue in The Times
F
I
N
I
C
K
Y

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The straight part
We know that "of fussy disposition" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case of fussy disposition = finicky.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does FINICKY mean?

FINICKY adjective
  1. (of a person) Fastidious and fussy; difficult to please; exacting, especially about details.
  2. Demanding; requiring above-normal care.

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