Cryptic crossword clue
A couple of knaves getting on top of one in nasty spots 7

The most common and most likely answer to this crossword clue is the 7 letter word PURPURA

P
U
R
P
U
R
A

Buddy explains!

The straight part
We know that "nasty spots" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case nasty spots = purpura.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

Crossword Answer definitions

PURPURA noun
  1. The appearance of red or purple discolorations on the skin that do not blanch when pressure is applied, caused by subdermal bleeding.

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