The most common and most likely answer to this crossword clue is the 7 letter word ADRENAL
I've seen this crossword clue in The Times
A
D
R
E
N
A
L
More clues leading to the result ADRENAL
- Affected ear and large gland
- A couple of ways around organ
- Doctor probes rear end of diva Lois, flipping close to the kidneys!
- Notice and learn about one sort of gland
- A medic’s way over somewhere near the kidneys
- A doctor on revolutionary course about certain glands
- Medic in A&E neatly removing every other gland
- A medic finding route back from glands
- A demise, primarily connected to kidney gland
- Lad near-damaging gland
Buddy explains!

The straight part
We know that "organ" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case organ = adrenal.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ADRENAL mean?
ADRENAL noun- An adrenal gland.
- Pertaining to the adrenal glands or their secretions.
- Near the kidneys.