Cryptic crossword clue
A couple take part in placebo therapy

The most common and most likely answer to this crossword clue is the 4 letter word BOTH

I've seen this crossword clue in The Guardian
B
O
T
H

Buddy explains!

The straight part
We know that "A couple" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case a couple = both.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BOTH mean?

BOTH pronoun
  1. Each of the two, or of the two kinds.
BOTH conjunction
  1. Including both of (used with and).
  2. Including all of (used with and).

Latest crossword clues with full explanations