Cryptic crossword clue
A curl Titian’s represented is true to life 12

The most common and most likely answer to this crossword clue is the 12 letter word NATURALISTIC

I've seen this crossword clue in The Times
N
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Buddy explains!

The straight part
We know that "true to life" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case true to life = naturalistic.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

Crossword Answer definitions

NATURALISTIC adjective
  1. Having the appearance of nature or realism; lifelike or realistic.
  2. Of or relating to philosophical or methodological naturalism.

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