Cryptic crossword clue
A fellow made a run for it after wife went on too much

The most common and most likely answer to this crossword clue is the 7 letter word WAFFLED

I've seen this crossword clue in Independent
W
A
F
F
L
E
D

Buddy explains!

The straight part
We know that "went on too much" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case went on too much = waffled.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does WAFFLED mean?

WAFFLED verb
  1. To smash.
WAFFLED verb
  1. (of birds) To move in a side-to-side motion and descend (lose altitude) before landing. Cf wiffle, whiffle.
  2. To speak or write vaguely and evasively.
  3. To speak or write at length without any clear point or aim.
  4. To vacillate.
  5. To rotate (one's hand) back and forth in a gesture of vacillation or ambivalence.
WAFFLED adjective
  1. Having a waffle-like pattern of intersecting creases.

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