The most common and most likely answer to this crossword clue is the 6 letter word ALSACE
I've seen this crossword clue in The Times
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More clues leading to the result ALSACE
- When to drink litres, going to brilliant wine-growing region
- Gang leader’s girl touring cool part of France
- Region noted for wine and beer — bottling wine mostly
- A fine fabric found around small area of France
- Beer bottles container for French region
- Wine region producing drink in pouch? Au contraire
- French region, almost too wonderful?
- Sadly slightly altered church in French region
- Like to go round lake, excellent wine-making region
- Man’s excellent knowledge about bad weather in border region
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.