The most common and most likely answer to this crossword clue is the 2 plus 4 letter word AT ODDS
I've seen this crossword clue in The Guardian
A
T
O
D
D
S
More clues leading to the result AT ODDS
- Barber cutting while arguing
- Calculates total, coming round to disagreeing
- On bad terms with Dorothy over splitting bills
- Quarrelling adds to confusion
- Quarrelling dads to wrestle
- A Fleet Street barber’s out of step
- Goes on about Tory leaders in disagreement
- A barber’s in dispute
- A third of directors did seem initially in disagreement
- A forerunner of Sassoon V gets to be in disagreement?
Buddy explains!
The straight part
We know that "out of step /out of step" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case out of step /out of step = at odds.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.