The most common and most likely answer to this crossword clue is the 9 letter word BLINDNESS
I've seen this crossword clue in Independent
B
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Buddy explains!

The straight part
We know that "A lack of vision" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case a lack of vision = blindness.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does BLINDNESS mean?
BLINDNESS noun- The condition of being blind; unable to see.
- Want of intellectual or moral discernment; mental darkness; ignorance, heedlessness.
- Concealment