Cryptic crossword clue
A large number — doesn’t matter which large number 4

The most common and most likely answer to this crossword clue is the 4 letter word MANY

I've seen this crossword clue in The Guardian
M
A
N
Y


Buddy explains!

The straight part
We know that "large number" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case large number = many.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MANY mean?

MANY noun
  1. A multitude; a great aggregate; a mass of people; the generality; the common herd.
  2. A considerable number.
MANY adjective
  1. A large number of; numerous.
MANY pronoun
  1. An indefinite large number of people or things.

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