Cryptic crossword clue
A little female, Sally, becoming panicky

The most common and most likely answer to this crossword clue is the 6 letter word AFRAID

I've seen this crossword clue in Independent
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This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does AFRAID mean?

AFRAID adjective
  1. (usually used predicatively, not attributively, be afraid) Impressed with fear or apprehension; in fear.
  2. Regretful, sorry.
  3. (used with for) Worried about, feeling concern for, fearing for (someone or something).

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