Cryptic crossword clue
A major‘s free to go after crossword setters! 2,4

The most common and most likely answer to this crossword clue is the 2 plus 4 letter word US OPEN

I've seen this crossword clue in The Guardian
U
S
O
P
E
N

Buddy explains!

The straight part
We know that "A major" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case a major = us open.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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