The most common and most likely answer to this crossword clue is the 6 letter word ATOPIC
I've seen this crossword clue in Financial Times
A
T
O
P
I
C
More clues leading to the result ATOPIC
- A subject for discussion making one hypersensitive
- Hypersensitive to allergy? Sunhat’s essential on temperature control
- Inclined to be hypersensitive, if there’s a theme
- A theme of allergic hypersensitivity
- A matter for discussion associated with hypersensitivity
- . A subject relating to one's predisposition for allergic reaction
Buddy explains!
The straight part
We know that "associated with hypersensitivity" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case associated with hypersensitivity = atopic.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ATOPIC mean?
ATOPIC adjective- Pertaining to or suffering from atopy.