Cryptic crossword clue
A medicinal tree earlier known as Margosa initially 4

The most common and most likely answer to this crossword clue is the 4 letter word NEEM

N
E
E
M


Buddy explains!

The straight part
We know that "A medicinal tree" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case a medicinal tree = neem.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does NEEM mean?

NEEM noun
  1. Azadirachta indica, a large, mostly evergreen tree from India, whose seeds yield the insecticide azadirachtin.

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