Cryptic crossword clue
A metaphor is mixed but its content is pithy

The most common and most likely answer to this crossword clue is the 8 letter word APHORISM

I've seen this crossword clue in The Guardian
A
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Buddy explains!

The straight part
We know that "its content is pithy" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case its content is pithy = aphorism.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does APHORISM mean?

APHORISM noun
  1. An original, laconic phrase conveying some principle or concept of thought.
APHORISM verb
  1. To speak or write aphorisms.

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