The most common and most likely answer to this crossword clue is the 4 plus 6 letter word BORN LEADER
B
O
R
N
L
E
A
D
E
R
Buddy explains!
The straight part
We know that "a natural for PM role?" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case a natural for pm role? = born leader.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.