The most common and most likely answer to this crossword clue is the 5 letter word SIXTY
I've seen this crossword clue in The Guardian
S
I
X
T
Y
Buddy explains!

The straight part
We know that "A number" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case a number = sixty.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SIXTY mean?
SIXTY numeral- The cardinal number occurring after fifty-nine and before sixty-one, represented in Roman numerals as LX and in Arabic numerals as 60.