Cryptic crossword clue
A radical actively cuts four in pieces 6

The most common and most likely answer to this crossword clue is the 6 letter word ACETYL

A
C
E
T
Y
L

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The cryptic/wordplay part
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This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does ACETYL mean?

ACETYL noun
  1. The univalent radical CH3CO- derived from acetic acid.

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