Cryptic crossword clue
A radical unknown line taken by new clergy 8

The most common and most likely answer to this crossword clue is the 8 letter word GLYCERYL

I've seen this crossword clue in The Guardian
G
L
Y
C
E
R
Y
L

Buddy explains!

The straight part
We know that "A radical" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case a radical = glyceryl.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does GLYCERYL mean?

GLYCERYL noun
  1. Either of the univalent, divalent or trivalent radicals derived from glycerol by removing hydrogen atoms from one, two or three hydroxyl groups

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