The most common and most likely answer to this crossword clue is the 8 letter word ALVEOLUS
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More clues leading to the result ALVEOLUS
Buddy explains!
The straight part
We know that "depression" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case depression = alveolus.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ALVEOLUS mean?
ALVEOLUS noun- A small cavity or pit.
- An anatomical structure that has the form of a hollow cavity, as: