The most common and most likely answer to this crossword clue is the 4 letter word WINE
I've seen this crossword clue in The Guardian
W
I
N
E
More clues leading to the result WINE
- Victory by English? Drink!
- Obtain energy drink
- Drink popular between bridge partners
- Complain, putting away hot drink
- Maybe red grouse, by the sound of it
- Gain point in table?
- Beef, not a slice of ham hock, say
- A taste of yellow in every red and white
- Drink you and I consume at home
- Home adopted by the Guardian
Buddy explains!

The straight part
We know that "red and white" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case red and white = wine.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does WINE mean?
WINE noun- An alcoholic beverage made by fermenting the juice of grapes.
- An alcoholic beverage made by fermenting the juice of fruits or vegetables other than grapes, usually preceded by the type of the fruit or vegetable; for example, "dandelion wine".
- A serving of wine.
- A dark purplish red colour; the colour of red wine.
- To entertain with wine.
- To drink wine.
- Wind.