The most common and most likely answer to this crossword clue is the 9 letter word INSOLUBLE
I've seen this crossword clue in The Daily Telegraph
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More clues leading to the result INSOLUBLE
Buddy explains!

The straight part
We know that "Able to resist crackers?" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case able to resist crackers? = insoluble.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does INSOLUBLE mean?
INSOLUBLE noun- Any substance that cannot be dissolved.
- That cannot be dissolved.
- That cannot be solved; unsolvable; insolvable.
- That cannot be explained; mysterious or inexplicable.
- That cannot be broken down or dispersed.