Cryptic crossword clue
Ace Joss and I wrestling with equine's indefinable quality 2,2,4,4

The most common and most likely answer to this crossword clue is the 2 plus 2 plus 4 plus 4 letter word JE NE SAIS QUOI

I've seen this crossword clue in The Times
J
E
N
E
S
A
I
S
Q
U
O
I

Buddy explains!

The straight part
We know that "indefinable quality" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case indefinable quality = je ne sais quoi.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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