Cryptic crossword clue
Action initiated by agent with Tom's ally to lose weight and attract girl 9

The most common and most likely answer to this crossword clue is the 9 letter word CATALYSIS

C
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Buddy explains!

The straight part
We know that "Action initiated by agent" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case action initiated by agent = catalysis.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CATALYSIS mean?

CATALYSIS noun
  1. The increase of the rate of a chemical reaction, induced by a catalyst.

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