Cryptic crossword clue
Address in Rome’s surprisingly close to Vatican 6

The most common and most likely answer to this crossword clue is the 6 letter word SERMON

I've seen this crossword clue in Financial Times
S
E
R
M
O
N


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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SERMON mean?

SERMON noun
  1. Religious discourse; a written or spoken address on a religious or moral matter.
  2. A lengthy speech of reproval.
SERMON verb
  1. To discourse to or of, as in a sermon.
  2. To tutor; to lecture.

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