Cryptic crossword clue
Advocate nurses with a bit of tenacity for place that’s isolated 9

The most common and most likely answer to this crossword clue is the 9 letter word BACKWATER

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Buddy explains!

The straight part
We know that "place that’s isolated" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case place that’s isolated = backwater.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BACKWATER mean?

BACKWATER noun
  1. The water held back by a dam or other obstruction
  2. A remote place; somewhere that remains unaffected by new events, progresses, ideas, etc.
  3. A rowing stroke in which the oar is pushed forward to stop the boat; see back water
BACKWATER verb
  1. To row or paddle a backwater stroke.
  2. To vacillate on a long-held position.

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