The most common and most likely answer to this crossword clue is the 6 plus 4 letter word TRAVEL SICK
I've seen this crossword clue in The Guardian
T
R
A
V
E
L
S
I
C
K
Buddy explains!
The straight part
We know that "Affected by movement" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case affected by movement = travel sick.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.