Cryptic crossword clue
Affected material finally cut 4

The most common and most likely answer to this crossword clue is the 4 letter word TWEE

I've seen this crossword clue in The Times
T
W
E
E


Buddy explains!

The straight part
We know that "Affected" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case affected = twee.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does TWEE mean?

TWEE adjective
  1. Overly quaint, dainty, cute or nice.

Latest crossword clues with full explanations