The most common and most likely answer to this crossword clue is the 7 letter word ZORILLA
I've seen this crossword clue in The Times
Z
O
R
I
L
L
A
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The straight part
We know that "African native" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case african native = zorilla.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ZORILLA mean?
ZORILLA noun- Ictonyx striatus, a small, carnivorous, nocturnal African mammal resembling a skunk.