Cryptic crossword clue
After ache is treated intention is to reverse deficiency in blood supply 9

The most common and most likely answer to this crossword clue is the 9 letter word ISCHAEMIA

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The cryptic/wordplay part
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What does ISCHAEMIA mean?

ISCHAEMIA noun
  1. Local disturbance in blood circulation due to mechanical obstruction of the blood supply (vasoconstriction, thrombosis or embolism).

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