Cryptic crossword clue
After commencement, heartache disturbed air tubes 8

The most common and most likely answer to this crossword clue is the 8 letter word TRACHEAE

T
R
A
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H
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A
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Buddy explains!

The straight part
We know that "air tubes" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case air tubes = tracheae.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does TRACHEAE mean?

TRACHEAE noun
  1. A thin-walled, cartilaginous tube connecting the larynx to the bronchi; the windpipe.
  2. Xylem vessel.
  3. One of the cuticle-lined primary tubes in the respiratory system of an insect, which extend throughout its body.

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