Cryptic crossword clue
After disruption, setter’s most brusque

The most common and most likely answer to this crossword clue is the 7 letter word TERSEST

T
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T

Buddy explains!

The straight part
We know that "most brusque" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case most brusque = tersest.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does TERSEST mean?

TERSEST adjective
  1. (by extension) Of speech or style: brief, concise, to the point.
  2. (by extension) Of manner or speech: abruptly or brusquely short; curt.
  3. Burnished, polished; fine, smooth; neat, spruce.

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