Cryptic crossword clue
After retreat of police, heartless killer’s less reliable 7

The most common and most likely answer to this crossword clue is the 7 letter word DICKIER

I've seen this crossword clue in The Guardian
D
I
C
K
I
E
R

Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DICKIER mean?

DICKIER adjective
  1. Doubtful, troublesome; in poor condition
DICKIER adjective
  1. Like a dick, foolish or obnoxious

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