Cryptic crossword clue
After setback, setter perhaps grasps anagram of pedometer as easy to get on with 4-8

The most common and most likely answer to this crossword clue is the 4 plus 8 letter word GOOD TEMPERED

I've seen this crossword clue in The Daily Telegraph
G
O
O
D
T
E
M
P
E
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E
D

Buddy explains!

The straight part
We know that "easy to get on with" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case easy to get on with = good tempered.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does GOOD TEMPERED mean?

GOOD TEMPERED adjective
  1. Not easily irritated; affable

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