Cryptic crossword clue
After work one retired may be given a new outlook 10

The most common and most likely answer to this crossword clue is the 10 letter word REORIENTED

I've seen this crossword clue in The Daily Telegraph
R
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O
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I
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Buddy explains!

The straight part
We know that "given a new outlook" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case given a new outlook = reoriented.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does REORIENTED mean?

REORIENTED verb
  1. To orient again; to make or become oriented after dislocation or disorientation.

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