Cryptic crossword clue
Agent for change to get a stomach churning over — dope? 7

The most common and most likely answer to this crossword clue is the 7 letter word MUTAGEN

I've seen this crossword clue in The Guardian
M
U
T
A
G
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Buddy explains!

The straight part
We know that "Agent for change/Agent for change" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case agent for change/agent for change = mutagen.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MUTAGEN mean?

MUTAGEN noun
  1. Any agent or substance that can cause genetic mutation.

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