Cryptic crossword clue
Agreed plan working on new vaccine

The most common and most likely answer to this crossword clue is the 10 letter word CONNIVANCE

I've seen this crossword clue in Independent
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The straight part
We know that "Agreed plan" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case agreed plan = connivance.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CONNIVANCE mean?

CONNIVANCE noun
  1. The process of conniving or conspiring.

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