The most common and most likely answer to this crossword clue is the 4 plus 6 letter word DATA MINING
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Buddy explains!
The straight part
We know that "large-scale analysis of information" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case large-scale analysis of information = data mining.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DATA MINING mean?
DATA MINING noun- A technique for searching large-scale databases for patterns; used mainly to find previously unknown correlations between variables that may be commercially useful.