The most common and most likely answer to this crossword clue is the 8 letter word DISORDER
I've seen this crossword clue in The Times
D
I
S
O
R
D
E
R
More clues leading to the result DISORDER
- Ailment riders do suffer
- Complaint caused by command from detective?
- Anarchy awfully sordid, sovereign beneath it
- Hell, with a group of religious folk creating chaos
- Lady’s request for food perhaps causing mayhem
- Fight in nick behind detectives
- Prepared to hedge in case rule about returning causes confusion
- In which mother might give Tom, her son, instruction after day one
- Range riders do create confusion
- Complaint I had rejected — more upset about diamonds
Buddy explains!

The straight part
We know that "Ailment" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case ailment = disorder.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DISORDER mean?
DISORDER noun- Absence of order; state of not being arranged in an orderly manner.
- A disturbance of civic peace or of public order.
- A physical or mental malfunction.
- To throw into a state of disorder.
- To knock out of order or sequence.