Cryptic crossword clue
Algiers at odds with old palace of Constantinople 8

The most common and most likely answer to this crossword clue is the 8 letter word SERAGLIO

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "palace of Constantinople" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case palace of constantinople = seraglio.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SERAGLIO mean?

SERAGLIO noun
  1. The palace of the Grand Seignior in Constantinople.
  2. The sequestered living quarters used by wives and concubines (odalisques) in a Turkish Muslim household.
  3. A brothel or place of debauchery.
  4. An interior cage or enclosed courtyard for keeping wild beasts.

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